Hyperbolic geometry of gene expression

Hyperbolic Geometry

Hyperbolic Geometry: Isometry Groups of Hyperbolic Space

The goal of this paper is twofold. First, it consists of an introduction to the basic features of hyperbolic geometry, and the geometry of an important class of functions of the hyperbolic plane, isometries. Second, it identifies a group structure in the set of isometries, specifically those that preserve orientation, and deals with the topological properties of their discrete subgroups. In the...

Geometry of gene expression dynamics

MOTIVATION A gene expression trajectory moves through a high dimensional space where each axis represents the mRNA abundance of a different gene. Genome wide gene expression has a dynamic structure, especially in studies of development and temporal response. Both visualization and analyses of such data require an explicit attention to the temporal structure. RESULTS Using three cell cycle tra...

Emergent Hyperbolic Network Geometry

A large variety of interacting complex systems are characterized by interactions occurring between more than two nodes. These systems are described by simplicial complexes. Simplicial complexes are formed by simplices (nodes, links, triangles, tetrahedra etc.) that have a natural geometric interpretation. As such simplicial complexes are widely used in quantum gravity approaches that involve a ...

Problems in Hyperbolic Geometry

The purpose of this document is to list some outstanding questions in the subject of hyperbolic geometry (real, complex, quaternionic, and the Cayley plane), with the primary focus on the latter three. This list was inspired by the problem sessions held at the conference on Complex Hyperbolic Geometry in Luminy (CIRM) in July of 2003. The questions are roughly grouped by similarity. The name(s)...